Biome V3 – Why Your Probiotics Aren’t Working 2


“This product has been a total life changer for me. I could feel it working almost immediately upon taking it and since then, I have a lot more energy and mental clarity. It’s also nice to find a prebiotic that doesn’t cause bloating.” – Matthew P. – California


“This product has been a total life changer for me. I could feel it working almost immediately upon taking it and since then, I have a lot more energy and mental clarity. It’s also nice to find a prebiotic that doesn’t cause bloating.” – Matthew P. – California

Why Your Probiotics Aren't Working​

And Why 99% Of All Others Will Make Symptoms Worse

Most probiotics simply don’t work.

And chances are, your probiotic is failing you too.

If you’re anything like me, you were hopeful for probiotics to change your life.

I desperately needed to eliminate the gas, bloating, indigestion and stomach troubles that slowly grew worse over time.

When I learned about probiotics, I had that light bulb moment, and rushed out to the store to give it a shot.

I took my first dose and went to sleep. Waking up the next day I felt nothing.

Hmm, okay…I figured maybe it will just take more time to let the good bacteria populate my gut.  

By the 3rd week, I was still feeling miserable. In fact, I felt worse.

The bloating and gas had become uncontrollable.

Then I figured maybe I needed different, more powerful strains. So switched brands.

One with over 100 billion CFU (colony forming units) per serving.

Nothing changed.

After just a few days, the diarrhea, headaches fatigue, and the gas and bloating had almost become debilitating at this point.

But my conviction in probiotics was so strong, I didn’t quit. Instead, I doubled down. 

I made it my mission to try as many different probiotics as I could find.

This led me down a rabbit hole of disappointment and suffering for years. Probiotics seemed like such a great idea, but why weren’t they working for me??

I must have tried over 100 brands of various probiotics, and even prebiotics, before giving up.

But I’m so glad I didn’t, because what happened next, changed my life.

4 Reasons Why Your Probiotics Aren’t Working

It took me 15 years to find out the 4 biggest reasons why most probiotics simply do not work:

1. Most probiotics contain a problematic ingredient.

One that actually increases gas/bloating, headaches and brain fog, for those suffering with chronic gut issues.

And companies add this ingredient thinking it’s beneficial for their typical customers – but chronic health sufferers aren’t their typical customers.

This nasty ingredient is a high FODMAP prebiotic, typically labeled as: inulin, FOS, GOS, XOS or chicory root.

If your probiotic contains any of these above prebiotics, they are likely making your condition much worse.

Now don’t get me wrong, these kinds of prebiotics are great for the typical person because they help feed the good bacteria in your gut, helping them further colonize the gut microbiome.

But they spell bad news for those of us with chronic health issues because they are a FODMAP food, which is an acronym, and it is a type of fiber that many people with chronic health issues have trouble digesting and only aggravate symptoms.  

*FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides and polyols, which are short-chain carbohydrates (sugars) that the small intestine absorbs poorly. Many people experience digestive distress after eating them.

I have a free resource at the end if you’re interested in learning why and how avoiding FODMAP foods can be a life-changer in itself.

For now, let’s look at the 2nd reason your probiotic isn’t working:

2. Many of the most popular probiotic strains actually raise histamine levels in the body.

This is a HUGE problem that not many people are talking about.

Histamine is a chemical found in some of the body’s cells.

It causes many of the symptoms of allergies, such as a runny nose, headaches or sneezing.

In an attempt to protect the body, the immune system starts a chain reaction that prompts some of the body’s cells to release histamine and other chemicals into the bloodstream.

The histamine then acts on a person’s eyes, nose, throat, lungs, skin, or gastrointestinal tract, causing allergy symptoms.

More than half of the lactobacillus strains (except L. plantarum) aggravate histamines in the body, causing severe reactions.

But did you know that there are probiotic strains that actually degrade histamines?

They naturally break them down in the body, helping soothe joint and muscle aches, fatigue, headaches and sleep issues?

We’ll look at which ones do that next…

Let’s look at the 3rd and final reason your probiotic isn’t working:

3. Most probiotics don’t include the ingredient that will neutralize the die-off toxins that begin drip-feeding your body while taking your probiotic.

This may be the biggest tip out of all of these.

Because, once you begin taking probiotics and they begin colonizing your gut, they are going to be kicking out tens of billions of bad bugs at once, such as candida fungus and other bacteria.

And these bad bugs don’t go quietly in the dark…

When they die off, they release potent neurotoxins called biofilms (LPS), which can wreak havoc on the body. Literally causing hundreds of symptoms including fatigue, muscle aches, brain fog and sleep issues.

And one of the most potent neurotoxins these bugs release is called acetaldehyde.

Acetaldehyde stays in your body – it does not get excreted like other toxins. A build up or accumulation of acetaldehyde can lead to joint discomfort, weak and achy muscles and fatigue.

Acetaldehyde is also what causes a hangover after a long night of drinking. 

But there is a quick fix for this – molybdenum.

It is one of the only things that will remove acetaldehyde from the body.

Molybdenum is a harmless trace mineral, which helps by converting the acetaldehyde into acetic acid. This harmless acid is then excreted by the body.

No more die-off symptoms!

4. Most will never make it to your gut alive.

The fact is, most probiotics are dead before they even reach your gut.

If they don’t die trying to get to your doorstep, they often die once they hit your stomach acid.

Yes, there are fancy coatings and new technology claiming to keep this from happening, but the fact is, the only true way to keep them alive so they reach your large intestine is by choosing the sturdiest strains.

Strains that can survive even the harshest of environments.

And it’s easy to do today because there are literally thousands of available strains to choose from.

By far, the sturdiest probiotics you will find are what’s known as spore probiotics (a.k.a. soil probiotics)

The true champion in this category is Bacillus subtilis.

Even NASA selected B. subtilis as the only strain capable of surviving over 3 years in space conditions.

B. subtilis has been given the GRAS designation by the FDA. “GRAS” is an acronym for the phrase Generally Recognized as Safe.





Hear from our latest customers

*Testimonials are individual accounts. Results may vary.

Why Your Probiotics Aren’t Working
It took me 15 years to find out the 4 biggest reasons why most probiotics simply do not work:


The Last Probiotic You'll Ever Need | 35 Billion CFU | Soil Probiotics | Fulvic Minerals


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“This product has been a total life changer for me. I could feel it working almost immediately upon taking it and since then, I have a lot more energy and mental clarity. It’s also nice to find a prebiotic that doesn’t cause bloating.” – Matthew P. – California

Hear from our latest customers

We don’t want you to pay for something that hasn’t totally transformed your life. We love witnessing healing in our customers – really, it’s why we do this. As a company, we base our success off of your well-being and increased vitality. If our products don’t benefit you, we want to know and improve it. 

No other probiotic contains both soil and lacto-based probiotics, FODMAP friendly prebiotics, fulvic minerals for addressing leaky gut and molybdenum to bind with toxins in the body to clear body aches, brain fog and fatigue.


Select Strains for Chronic Illness

Six specialized probiotic strains for chronic illness symptoms that help to fight body aches, fatigue, and brain fog.


FODMAP Friendly Prebiotics

FODMAP friendly prebiotic fiber that feeds your friendly bacteria all without gas or bloating. Monash University-approved!


Fulvic Mineral Blend

Helps fight fatigue, body pain, and brain fog, and protects you from leaky gut by supporting tight junctions.


Molybdenum for Toxins

This essential mineral binds to and breaks down the #1 toxin responsible for fatigue, brain fog, and body aches.

Biome V3

Tummy Tolerated

Probiotic and prebiotic strains that even the most sensitive tummies can tolerate.

Hearty Strains

Contains high-survivability spore and lacto/bifido probiotic strains.

Fulvic Minerals

Fulvic minerals have over a dozen health benefits including binding toxins, keeping tight junctions healthy (leaky gut), fighting candida, and supporting energy levels.

Toxin Binding

The essential mineral molybdenum in Biome V3 breaks down acetaldehyde. Acetaldehyde is the main toxin that candida and bacteria pollute our bodies with, causing fatigue, headaches, and leaky gut symptoms.

Have All-Day Energy Again

The toxins from an unhealthy gut can deplete your energy levels. When your gut is balanced, everything else falls into place.

Doctor Trusted

We have MDs, naturopaths, and acupuncturists from all disciplines using Biome V3 with their patients.

Guaranteed to Work or Your Money Back

We're only happy if you are happy. Period.

Not Just A Supplement

Biome V3 is not just a supplement - it's a total gut health system.

100% USA Based Laboratories

Native Formulas is a proud USA manufacturer. All of our products are manufactured in FDA registered and GMP certified facilities.

Real Reviews From Real Customers


Based on 33 Reviews

94%  of reviewers would recommend this product to a friend

Great customer relations and effective product

June 12, 2024

As a medical professional and researcher, I am careful of the companies I deal with. I bought the Biome V3 because I mysteriously got the horrible C Diff infection in my colon. The product has been a great adjunct to my natural approach to this nightmare infection. Use the V3 , some black seed oil and stay with it. Consult you Dr

Well, there is more. I accidentally chose auto ship and did not want that and Tera was an angel in her quick and professional response in cancelling that shipping choice. Thanks again for a great experience with your company


Response from Native Formulas

Thank you for sharing your experience with Biome V3, Jeff. We’re so happy you have been able to find them effective.

*Testimonials are individual accounts. Results may vary

Biome V3 has played a major role in turning my life around

March 3, 2024

I suffered for 12 years with leaky gut and Biome V3 has played a major role in turning my life around again. It’s an extremely well thought out formula that reconditions the gut back into balance. Prebiotics, probiotics and fulvic minerals are a winning combination.

Mark B.

Response from Native Formulas

Thank you for your valuable feedback, Mark!

*Testimonials are individual accounts. Results may vary

The only thing that has ever truly helped me

February 12, 2024

I have always struggled with digestive issues. Biome V3 is the only thing that has ever truly helped me

Samantha K.

Response from Native Formulas

Yes! We agree and take this every day as well. Thanks for submitting

*Testimonials are individual accounts. Results may vary

More energy, mental clarity and I'm a lot more regular

January 20, 2024

I feel so much better since doing a low-FODMAP diet and Biome V3 has helped me quickly rebuild my gut microbiome. I have a lot more energy, mental clarity and I’m a lot more regular since taking it daily. You have a customer for life.

Jill P.

Response from Native Formulas

That’s wonderful, Jill. Thank you for sharing with us!

*Testimonials are individual accounts. Results may vary

I love Biome V3

December 21, 2023

I just wanted to share my success with your product Biome V3. I feel that I’ve finally found a probiotic that I can actually take without causing stomach upset. I really do notice the difference when I don’t take it and I’ve ran out a few times, which is how I know! I’m finally set up on auto renew, which is a great feature since I save $10, per bottle. 5 stars


Response from Native Formulas

Emily, thank you for sharing! Biome V3 was made for folks just like yourself.

*Testimonials are individual accounts. Results may vary.

Frequently Asked Questions

Biome V3 is the hardest working probiotic you can find. It’s actually a symbiotic with added benefits. Meaning it contains FODMAP friendly pre-biotics, histamine degrading soil and lacto-based probiotics, fulvic acid for energy production and molybdenum to support detoxification.



Yes, absolutely! Biome V3 was designed to work synergistically with Restore 3 and can be taken during all 3 phases of the Restore 3 Program.


Orders are processed in the order they are received. All orders are shipped within 24 business hours via USPS First Class, Priority Mail, UPS, FedEx, or DHL and should reach you within 4-6 business days.


We currently only ship within the United States.


If you are unsatisfied with your purchase, you may return your whole order within 60 days from the purchase date to receive a refund on your product. Refunds are limited to one order per customer. You must include all bottles, whether opened or not. We do not refund any shipping costs.

Native Formulas Address
7040 Avenida Encinas STE 104-906
Carlsbad, CA 92011

Refund does not include any shipping and handling charges you may incur while shipping back.

We process refunds as quickly as possible. However, please be advised that it may take up to 14 business days to receive a refund after we have received your return.


Yes, shipping and handling is free for all orders and orders are processed in the order they are received. All orders placed before 3pm EST M-S are shipped out same day via USPS First Class, Priority Mail, UPS, FedEx or DHL.


Biome V3 contains 6 histamine degrading probiotic strains, our FODMAP friendly prebiotic called Sunfiber, fulvic acid and the essential mineral molybdenum.


6 to 8 weeks is the minimum length of time to allow results, however, many people report benefits within the first few days of taking Biome V3. The gut microbiome is very massive. If you were to stretch it all out, it would cover a tennis court. This is why it takes longer for gut changes to happen.


The ideal way to take Biome V3 is once in the morning and once in the evening. You can take up to 8 capsules per day.


Biome V3 is manufactured right here in the United States in an FDA-inspected facility. Unfortunately, many natural supplements are manufactured in China and other overseas countries, which currently has a poor record for creating safe natural supplements. We are proud to manufacture Biome V3 here in the United States.


Additional information


Discount Autoship, 3 Pack Sale, Single Bottle, Restore Mg

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Ready To Refresh And Recharge?

Get a full refund if you don’t love Native Formulas.

Rest assured. You can try Native Formulas for 60 days risk-free.

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