Biome V3 – Why Your Probiotics Aren’t Working 2 (Fb) -Older


“This product has been a total life changer for me. I could feel it working almost immediately upon taking it and since then, I have a lot more energy and mental clarity. It’s also nice to find a prebiotic that doesn’t cause bloating.” – Matthew P. – California


“This product has been a total life changer for me. I could feel it working almost immediately upon taking it and since then, I have a lot more energy and mental clarity. It’s also nice to find a prebiotic that doesn’t cause bloating.” – Matthew P. – California

Why Your Probiotics Aren't Working​

And Why 99% Of All Others Usually Make Symptoms Worse

Most probiotics simply do not work.

And the chances are, your probiotic is failing you.

If you’re anything like me, you may have been hopeful for probiotics to change your life.

When I was unwell, I desperately needed a solution to the gas, bloating, indigestion, and stomach troubles that slowly grew worse over time.

When I learned about probiotics, I had that ‘light bulb’ moment, and rushed out to the store to pick up the highest quality probiotic I could find.

I took my first dose and went to sleep. Waking up the next day, I felt nothing.

Hmm, okay…I figured maybe it will just take longer to let the good bacteria populate my gut.  

By the 3rd week, I still felt miserable. Moreover, I felt worse.

The bloating and gas had become unbearable.

I decided then that perhaps I needed different, more powerful strains. So I switched brands.

One with over 100 billion CFU (colony forming units) per serving.

Nothing changed.

After just a few days, the diarrhea, headaches fatigue, and the gas, and bloating had become nearly debilitating.

My sleep was interrupted, I couldn’t concentrate on simple tasks and I was always in pain.

Despite my progressing symptoms, my conviction in the relief probiotics could provide remained strong. I didn’t quit. Instead, I doubled down. 

I made it my mission to try as many different probiotics as I could find.

For years, this led me down a rabbit hole of disappointment and suffering. Probiotics seemed like such a great idea – why weren’t they working for me??

I must have tried over 100 brands of various probiotics, and even prebiotics, before almost giving up.

I’m so glad I didn’t, because what happened next, changed my life.

Why Your Probiotics Aren’t Working

After struggling for 15 years I discovered the 4 biggest reasons why most probiotics simply do not work:

1. Most probiotics contain a problematic ingredient: FODMAPs

For those suffering with chronic gut issues, this ingredient actually increases gas, bloating, headaches, and brain fog.

And companies add this ingredient thinking it’s beneficial for their typical customers – but chronic health sufferers aren’t their typical customers.

This nasty ingredient is a high FODMAP prebiotic, typically labeled as: inulin, FOS, GOS, XOS or chicory root.

*FODMAP stands for Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols, which are short-chain carbohydrates (sugars) that the small intestine cannot absorb well. Many people experience digestive distress after eating foods with these ingredients.

If your probiotic contains any of these above prebiotics, it is likely making your condition much worse.

Now don’t get me wrong, these kinds of prebiotics are great for the average consumer because they help feed the good bacteria in your gut, helping them to further colonize the gut microbiome.

But common prebiotics spell bad news for those of us with chronic health issues because they are a FODMAP food, and it is a type of fiber that many people with chronic health issues have trouble digesting and only aggravate symptoms.  

If you’re interested in learning why and how avoiding FODMAP foods can be a life-changer in itself, please refer to my free resource at the bottom of this page.

Now, let’s look at the 2nd reason your probiotic isn’t working:

2. Many of the most popular probiotic strains actually raise histamine levels in the body.

This is a HUGE problem that not many people are talking about.

Histamine is a chemical found in some of the body’s cells.

It causes many allergy symptoms, such as a runny nose, headaches, or sneezing.

In an attempt to protect the body, the immune system starts a chain reaction that prompts some of the body’s cells to release histamine and other chemicals into the bloodstream.

The histamine then acts on a person’s eyes, nose, throat, lungs, skin, or gastrointestinal tract, causing allergy symptoms.

More than half of the lactobacillus strains – featured in many probiotic supplements – (except L. plantarum) aggravate histamines in the body, causing severe reactions.

But did you know that there are probiotic strains that actually degrade histamines?

These strains naturally break down histamines in the body, helping soothe joint and muscle aches, fatigue, headaches and sleep issues.

We’ll look at which ones do that next…

Let’s look at the third and final reason your probiotic isn’t working:

3. A good probiotic will end up killing off bad bacteria. It must have an ingredient that will help neutralize the 'die-off' toxins that are produced during this process.

This may be the biggest tip out of all of these.

Because, once you begin taking probiotics and they begin to colonize your gut, they will be kicking out tens of billions of harmful bugs at once, such as candida fungus and other bacteria.

And these bad bugs don’t go quietly in the dark…

When they die off, they release potent neurotoxins called biofilms (LPS or lipopolysaccharides), which can wreak havoc on the body. Literally causing hundreds of symptoms including fatigue, muscle aches, brain fog and sleep issues.

And one of the most potent neurotoxins these bugs release is called acetaldehyde.

Unlike many toxins, which the body excretes, acetaldehyde stays in your body. It does not get excreted like other bodily toxins. A build up or accumulation of acetaldehyde can lead to joint discomfort, weak and achy muscles and fatigue.

Acetaldehyde is also what causes a hangover after a long night of drinking. 

But there is a quick fix for this – molybdenum.

Molybdenum is one of the only substances that will remove acetaldehyde from the body.

It is a harmless trace mineral: it supports you by converting the acetaldehyde into acetic acid. This harmless acid is then excreted by the body.

No more die-off symptoms!

4. Most good bacteria will never make it to your gut alive.

The fact is, most probiotics are dead before they even reach your gut.

If they don’t die trying to get to your doorstep, they likely will once they hit your stomach acid.

Yes, there are fancy coatings and new technology claiming to keep this from happening. But the truth is, the only way to keep probiotic strains alive so they reach your large intestine is by choosing the sturdiest strains.

Strains that can survive even the harshest of environments.

And it’s easy to do – there are literally thousands of currently available strains to choose from.

By far, the sturdiest probiotics you will find are what’s known as spore probiotics (a.k.a. soil probiotics).

The true champion in this category is Bacillus subtilis.

Even NASA selected B. subtilis as the only strain capable of surviving over three years in space conditions.

B. subtilis has been given the GRAS designation by the FDA. “GRAS” is an acronym for the phrase Generally Recognized as Safe.

If you can include these 4 factors, there is no reason why your probiotic will fail you.

This is exactly why we developed Biome V3. And why hundreds of people are already experiencing the benefits of a true, working probiotic formula. 

But don’t take our word for it. Hear what our latest customers have to say about it below:


Hear from our latest customers

*Testimonials are individual accounts. Results may vary.

The Last Probiotic You'll Ever Need | 35 Billion CFU | Soil Probiotics | Fulvic Minerals


$49.00-$159  Free Shipping

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“This product has been a total life changer for me. I could feel it working almost immediately upon taking it and since then, I have a lot more energy and mental clarity. It’s also nice to find a prebiotic that doesn’t cause bloating.” – Matthew P. – California

Hear from our latest customers

We don’t want you to pay for something that hasn’t totally transformed your life. We love witnessing healing in our customers – really, it’s why we do this. As a company, we base our success off of your well-being and increased vitality. If our products don’t benefit you, we want to know and improve it. 

No other probiotic contains both soil and lacto-based probiotics, FODMAP friendly prebiotics, fulvic minerals for addressing leaky gut and molybdenum to bind with toxins in the body to clear body aches, brain fog and fatigue.


We Use Probiotics for Chronic Illness

Specialized strains for chronic illness symptoms that fight leaky gut, fatigue & brain fog.


FODMAP Friendly Prebiotics

Feeds your friendly bacteria all without gas or bloating. Monash University-approved!


Fulvic Mineral Blend

Helps fight fatigue, body pain, and brain fog, and protects you from leaky gut by supporting tight junctions.


Molybdenum for Toxins

This essential mineral binds to and breaks down the #1 toxin responsible for fatigue, brain fog and body aches.

Biome V3

Tummy Tolerated

Probiotic and prebiotic strains that even the most sensitive tummies can tolerate.

Hearty Strains

Contains high-survivability spore and lacto/bifido probiotic strains.

Fulvic Minerals

Fulvic minerals have over a dozen health benefits including binding toxins, keeping tight junctions healthy (leaky gut), fighting candida, and supporting energy levels.

Toxin Binding

The essential mineral molybdenum in Biome V3 breaks down acetaldehyde. Acetaldehyde is the main toxin that candida and bacteria pollute our bodies with, causing fatigue, headaches, and leaky gut symptoms.

Have All-Day Energy Again

The toxins from an unhealthy gut can deplete your energy levels. When your gut is balanced, everything else falls into place.

Doctor Trusted

We have MDs, naturopaths, and acupuncturists from all disciplines using Biome V3 with their patients.

Guaranteed to Work or Your Money Back

We're only happy if you are happy. Period.

Not Just A Supplement

Biome V3 is not just a supplement - it's a total gut health system.

100% USA Based Laboratories

Native Formulas is a proud USA manufacturer. All of our products are manufactured in FDA registered and GMP certified facilities.


Based on 143 Reviews

92%  of reviewers would recommend this product to a friend

Real Reviews From Real Customers

This shit WORKS!!

Rated 5 out of 5
September 28, 2023

I have been on this product for the good part of a year. The stuff works but I feel like it may bc less effective over time due to resistance factor. truth is I need to maintain more consistency understanding that even if I experience temporary relief until I suffer a food intolerance reaction , that maintaining consistency daily is an absolute must. Its been enormous trial and error over exstensive suffering from severe brain fog, depression, lethargy, sleep disturbances, mood disorders and food intolerance. The bottom line is that this is among the finest products I have tried over years over struggling and I keep coming back to Restore 3, after trying other alternatives from biocidin, oregano oil and colloidal silver. Native Formula is the most effective of these alternatives without a doubt. More determined than ever to maintain consistency in dosage to allow for colonization over whatever time is necessary. To say this 45- year nightmare has been a struggle would be a huge understatement. I owe Native formulas MY LIFE!


Response from Native Formulas

Wow, Gary. We truly feel like you are the reason why we do this and are so happy to read this review. Congratulations on ending your struggle!!

*Testimonials are individual accounts. Results may vary.

Helping my wife

Rated 5 out of 5
September 17, 2023

I found these through a friend who is a doctor and deals with biofilm stuff with her patients. She is following the protocol with major improvement. Before she was spending a lot of time in bed or on the couch, now she is able to move a lot easier and with significantly less pain.

Chris Dole

Response from Native Formulas

We’re so glad you gave Restore 3 a try and followed through with the whole protocol! It works if you work it.

*Testimonials are individual accounts. Results may vary

Side Effects

Rated 2 out of 5
September 4, 2023

I’ve been taking Restore 3 for almost 2 weeks and I’ve been noticing a sharp increase in my symptoms, especially brain fog, lethargy and pain all over. I can’t continue with this program. It’s too bad, I really was hoping this would be the solution.


Response from Native Formulas

Hi Rebecca,

I’m sorry to hear it’s been challenging to stick with the protocol. It most definitely sounds like a Herx reaction. I hope you find a solution that better suits you soon. Hopefully, you still find the reading material useful and find benefit by following the lifestyle and dietary guidelines that have helped us.

*Testimonials are individual accounts. Results may vary

This Product Should Be Given An Award.

Rated 5 out of 5
August 22, 2023

I didn’t expect something like this to work the way it did for me, but I am astounded at the results from taking this. I used to have terrible upset stomach that got progressively worse for me. Bloating, cramping and general unease were my symptoms. A friend told me about this product and how it helped her gut issues and I decided to give it a try. Within the first dose, I began to notice a decrease in symptoms and by the end of the week, I had forgotten about my digestive troubles. They just were non-existent. I see why it’s called Restore. It seemed to do just that for my digestive system. Very satisfied with my results.

Sandra Toro

Response from Native Formulas

Wow, thank you for the wonderful review, Sandra! It’s reviews like this that give us the inspiration to continue doing what we do. We’re not looking for rewards, we just want to help you get better.

*Testimonials are individual accounts. Results may vary.

Get This - It Works Really Well !

Rated 5 out of 5
August 15, 2023

I have suffered with fms related digestive issues for 20+ years. I began the 2 week dietary cleans protocol on May 15th, 2023 and started with Restore 3 July 1st – which showed immediate positive results for me. Subsequently I had a setback as I contracted pneumonia on an Alaskan cruise June 7th and the accompanying antibiotics wiped all the bacteria out, good and bad. I started over and want to say today on July 20th I am feeling fantastic … digestive issues and morning nausea are gone! Thank you for figuring this out and sharing the solution with us! God Bless You …

Hershell Mann

Response from Native Formulas

Yay, Hershell!! We are so thrilled to get this feedback from you 🙂 Thank you for taking the time to let us know!

*Testimonials are individual accounts. Results may vary

Frequently Asked Questions

Biome V3 is the hardest working probiotic you can find. It's actually a symbiotic with added benefits. Meaning it contains FODMAP friendly pre-biotics, histamine degrading soil and lacto-based probiotics, fulvic acid for energy production and molybdenum to support detoxification.

Yes, absolutely! Biome V3 was designed to work synergistically with Restore 3 and can be taken during all 3 phases of the Restore 3 Program.

Orders are processed in the order they are received. All orders are shipped within 24 business hours via USPS First Class, Priority Mail, UPS, FedEx, or DHL and should reach you within 4-6 business days.


We currently only ship within the United States.

If you are unsatisfied with your purchase, you may return your whole order within 60 days from the purchase date to receive a refund on your product. Refunds are limited to one order per customer. You must include all bottles, whether opened or not. We do not refund any shipping costs.

Native Formulas Address
7040 Avenida Encinas STE 104-906
Carlsbad, CA 92011

Refund does not include any shipping and handling charges you may incur while shipping back.

We process refunds as quickly as possible. However, please be advised that it may take up to 14 business days to receive a refund after we have received your return.

Yes, shipping and handling is free for all orders and orders are processed in the order they are received. All orders placed before 3pm EST M-S are shipped out same day via USPS First Class, Priority Mail, UPS, FedEx or DHL.

Biome V3 contains 6 histamine degrading probiotic strains, our FODMAP friendly prebiotic called Sunfiber, fulvic acid and the essential mineral molybdenum.

6 to 8 weeks is the minimum length of time to allow results, however, many people report benefits within the first few days of taking Biome V3. The gut microbiome is very massive. If you were to stretch it all out, it would cover a tennis court. This is why it takes longer for gut changes to happen.

The ideal way to take Biome V3 is once in the morning and once in the evening. You can take up to 8 capsules per day.

Biome V3 is manufactured right here in the United States in an FDA-inspected facility. Unfortunately, many natural supplements are manufactured in China and other overseas countries, which currently has a poor record for creating safe natural supplements. We are proud to manufacture Biome V3 here in the United States.

Additional information


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Get a full refund if you don’t love Native Formulas.

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